John Parker, PhD

contact@johnaparker.com·johnaparker.com·GitHub·Chicago, IL

Experience

Director of Software Engineering
Evozyne
Jan 2026 - Present

Leading software engineering, data platform, and AI strategy at a biotech startup, aligning cloud infrastructure and AI initiatives with business goals

  • Established Agentic AI systems on AWS Bedrock and Databricks using Claude Agent SDK, Agent Skills, and MCP, with knowledge base connectors to Confluence and electronic lab notebooks
  • Drove company-wide Claude Enterprise adoption as a change management program across Data Science, Lab Departments, IT, and Business, anchored by security guardrails, responsible-use training, and PR and documentation governance gates
  • Managed cross-platform budget forecasting and scaling across AWS, Databricks, and Claude AI, including spend attribution by department
  • Established company-wide data strategy and SOPs consolidating fragmented lab and sequence data into a unified bronze/silver/gold pipeline on S3, Databricks Declarative Pipelines, and Lakebase
Software Engineering Manager
Evozyne
Dec 2023 - Dec 2025

Managed a software engineering team at a biotech startup, overseeing cloud-based deep learning and bioinformatics workflows while providing platform support across data scientists, lab scientists, and leadership

  • Led company-wide migration to the Databricks platform, centralizing data and enabling self-service analytics
  • Partnered with IT to enable real-time lab data ingestion of many instruments using AWS S3 File Gateway and Spark Declarative Pipelines
  • Transitioned team focus from infrastructure maintenance toward application and data engineering with direct business impact
Software Engineer
Evozyne
Jun 2022 - Nov 2023

Developed and maintained a greenfield machine learning software platform on AWS to enable and support Data Science workloads

  • Architected greenfield ML platform on Kubernetes (EKS) with Metaflow and Argo Workflows, supporting parallel GPU training jobs for VAE and transformer models
  • Unified ML/SWE repositories into a trunk-based monorepo with GitHub Actions CI/CD, merge queues, and feature flags for continuous deployments
  • Migrated data warehouse to Apache Iceberg lakehouse with FastAPI/Panel stack for dataset streaming and cross-team data sharing
  • Partnered with NVIDIA as early access collaborator to integrate BioNeMo T5 LLMs into custom VAE architecture on Kubernetes
  • Contributed to Netflix's open-source Metaflow, resolving an issue in its Argo Workflow generator
Computational Scientist
Research Computing Center, University of Chicago
Mar 2021 - May 2022

Provided software development, training, and system administration for a Linux-based high performance computing (HPC) cluster serving University researchers

  • Benchmarked CPU and GPU performance on next-gen HPC cluster with NVIDIA A100 (MIG), AMD, and Intel hardware using CUDA and MPI.
  • Built multi-GPU molecular dynamics framework using JAX and MPI, scaling ensemble simulations beyond single-node limits.
  • Led interactive HPC workshops on SLURM, parallel Python/MPI, and high-performance computing concepts.
Postdoctoral Scholar
University of Chicago
Sep 2020 - Feb 2021

Conducted computational physics research spanning simulation development, software publication, and academic scholarship.

  • Published cross-platform Python & C++ simulation packages for electrodynamics and hydrodynamics, using CMake and pybind11
  • Co-authored over a dozen peer-reviewed publications with collaborators at the University of Chicago, Argonne National Laboratory, and partner academic institutions.

Education

University of Chicago
Chicago, IL
Sep 2014 - Aug 2020

PhD Physics

Computational physics research in Norbert Scherer's Lab. Thesis "Collective Electrodynamic Excitations and Non-conservative Dynamics in Optical Matter and Meta-atom Systems"

Georgia Institute of Technology
Atlanta, GA
Aug 2011 - May 2014

BS Physics, Minor in Mathematics

Computational physics research in Daniel Goldman's Complex Rheology And Biomechanics (CRAB) lab, studying the physical properties of granular materials.

Skills

AWS & Cloud
Kubernetes (EKS)ECSEC2RDSS3VPCTerraformArgoCDArgo Workflows
Databricks
Lakeflow Declarative PipelinesLakeflow JobsDelta Lake (OLTP)Lakebase (OLAP)Apache Spark
Python
NumPyScipyPandasPyTorchFastAPIMetaflowSQLAlchemyAlembicPanelStreamlitDashuvpixi
C++
CMakeEigenGSLCUDANVIDIA OptiXpybind11 & nanobind
Agentic AI
Claude CodeAWS BedrockDatabricks GenieAgents with Claude Agent SDK
Management and Leadership
Cloud budget managementLinear project managementStandard Operating Procedures authorshipTeaching and talent growth

Open Source

Loom
Rust

Loom is a Rust TUI control center for managing git worktrees and agentic workflows, supporting Claude Code, GitHub, and Linear

FPlanck
Python

FPlanck is a Python library for numerically solving the Fokker-Planck partial differential equation (also known as the Smoluchowski equation) in N dimensions using a matrix numerical method

MiePy
Python C++

MiePy is Python and C++ module to solve Maxwell's equations for a cluster of particles using the generalized multiparticle Mie theory (GMMT)

StokeD
Python

StokeD solves the Stokesian Dynamics equations for N interacting particles, a generalization of Brownian dynamics that includes hydrodynamic coupling interactions

Publications

Symmetry breaking-induced N-body electrodynamic forces in optical matter systems
Nature Communications · 2025

John Parker, Spoorthi Nagasamudram, Curtis Peterson, Yanzeng Li, Sina Soleimanikahnoj, Stuart A Rice, Norbert F Scherer

ProT-VAE: Protein Transformer Variational AutoEncoder for Functional Protein Design
PNAS · 2025

Emre Sevgen, Joshua Moller, Adrian Lange, John Parker, Sean Quigley, Jeff Mayer, Poonam Srivastava, Sitaram Gayatri, David Hosfield, Maria Korshunova, Micha Livne, Michelle Gill, Rama Ranganathan, Anthony B. Costa, Andrew L. Ferguson

Non-Equilibrium Dynamics and Non-Gaussian Fluctuations of an Optical Matter System Manifesting Pseudorotation
ACS Nano · 2025

Shiqi Chen, John A. Parker, John Linderman, Curtis W. Peterson, Emmanuel Valenton, Stuart A. Rice, Andrew L. Ferguson, Norbert F. Scherer

Optical trapping with optical magnetic field and photonic Hall effect forces
Nature Communications · 2025

Yanzeng Li, Emmanuel Valenton, Spoorthi Nagasamudram, John Parker, Marcos Perez, Uttam Manna, Mahua Biswas, Stuart A Rice, Norbert F Scherer

PySAGES: flexible, advanced sampling methods accelerated with GPUs
npj Computational Materials · 2024

Pablo F Zubieta Rico, Ludwig Schneider, Gustavo R Pérez-Lemus, Riccardo Alessandri, Siva Dasetty, Trung D Nguyen, Cintia A Menéndez, Yiheng Wu, Yezhi Jin, Yinan Xu, Samuel Varner, John A Parker, Andrew L Ferguson, Jonathan K Whitmer, Juan J de Pablo

Electrodynamic Interference and Induced Polarization in Nanoparticle-Based Optical Matter Arrays
The Journal of Physical Chemistry C · 2024

Curtis Peterson, John Parker, Emmanuel Valenton, Yuval Yifat, Shiqi Chen, Stuart A Rice, Norbert F Scherer

Understanding and design of non-conservative optical matter systems using Markov state models
Molecular Systems Design & Engineering · 2022

Shiqi Chen, John A Parker, Curtis W Peterson, Stuart A Rice, Norbert F Scherer, Andrew L Ferguson

Data-driven reaction coordinate discovery in overdamped and non-conservative systems: application to optical matter structural isomerization
Nature Communications · 2021

Shiqi Chen, Curtis W. Peterson, John Parker, Stuart A. Rice, Andrew L. Ferguson, Norbert F. Scherer

Facile measurement of the rotation of a single optically trapped nanoparticle using the diagonal ratio of a quadrant photodiode
ACS Photonics · 2021

Yuval Yifat, John Parker, Tian-Song Deng, Stephen K. Gray, Stuart A. Rice, Norbert F. Scherer

Optical matter machines: angular momentum conversion by collective modes in optically bound nanoparticle arrays
Optica · 2020

John Parker, Curtis W. Peterson, Yuval Yifat, Stuart A. Rice, Zijie Yan, Stephen K. Gray, Norbert F. Scherer

Excitation of nonradiating anapoles in dielectric nanospheres
Physical Review Letters · 2020

John Parker, Hiroshi Sugimoto, Brighton Coe, Daniel Eggena, Minoru Fujii, Norbert F. Scherer, Stephen K. Gray, Uttam Manna

Discrete pH-responsive plasmonic actuators via site-selective encoding of nanoparticles with DNA triple helix motif
Cell Reports Physical Science · 2020

Kyle J. Gibson, Aleksander Prominski, Margaret S. Lee, Timothy M. Cronin, John Parker, Yossi Weizmann

Designing "metamolecules" for photonic function: reduced back scattering
Physica Status Solidi B · 2020

Tian-Song Deng, John Parker, Yutaro Hirai, Nolan Shepherd, Hiroshi Yabu, Norbert F. Scherer

Controlling the dynamics and optical binding of nanoparticle homodimers with transverse phase gradients
Nano Letters · 2019

Curtis W. Peterson, John Parker, Stuart A. Rice, Norbert F. Scherer

Dark plasmon modes in symmetric gold nanoparticle dimers illuminated by focused cylindrical vector beams
Journal of Physical Chemistry C · 2018

Tian-song Deng, John Parker, Yuval Yifat, Nolan Shepherd, Norbert F. Scherer

Dynamics of the optically directed assembly and disassembly of gold nanoplatelet arrays
Nano Letters · 2018

Delphine Coursault, Nishant Sule, John Parker, Ying Bao, Norbert F. Scherer

Crossover from positive to negative optical torque in mesoscale optical matter
Nature Communications · 2018

Fei Han, John Parker, Patrick McCormack, Yuval Yifat, Stephen K. Gray, Norbert F. Scherer, Zijie Yan

Reactive optical matter: light-induced motility in electrodynamically asymmetric nano-scale scatterers
Light: Science & Applications · 2018

Yuval Yifat, Delphine Coursault, Curtis W. Peterson, John Parker, Ying Bao, Stephen K. Gray, Stuart A. Rice, Norbert F. Scherer

Optical magnetism in core-satellite nanostructures excited by vector beams
SPIE · 2018

John Parker, Stephen K. Gray, Norbert F. Scherer

Selective induction of optical magnetism
Nano Letters · 2017

Uttam Manna, Jung-hoon Lee, Tian-Song Deng, John Parker, Nolan Shepherd, Yossi Weizmann, Norbert F. Scherer