John Parker, PhD

contact@johnaparker.com·johnaparker.com·GitHub·Chicago, IL

Experience

Software Engineering Manager
Evozyne
Dec 2023 - Present

Led a software engineering team at a biotech startup, overseeing cloud-based deep learning and bioinformatics workflows while providing platform support across data scientists, lab scientists, and leadership

  • Led company-wide migration to the Databricks platform
  • Partnered with IT to enable real-time lab data ingestion of many instruments using AWS S3 File Gateway and Spark Declarative Pipelines
  • Authored company-wide SOPs for lab data storage, sequence database ingestion, and software engineering best practices
  • Built enterprise Agentic AI strategies using Claude Code, AWS Bedrock, and Databricks Genie
Software Engineer
Evozyne
Jun 2022 - Nov 2023

Developed and maintained a greenfield machine learning software platform on AWS to enable and support Data Science workloads

  • Architected greenfield ML platform on Kubernetes (EKS) with Metaflow and Argo Workflows, supporting parallel GPU training jobs for VAE and transformer models
  • Unified ML/SWE repositories into a trunk-based monorepo with GitHub Actions CI/CD, merge queues, and feature flags for continuous deployments
  • Migrated data warehouse to Apache Iceberg lakehouse with FastAPI/Panel stack for dataset streaming and cross-team data sharing
  • Partnered with NVIDIA as early access collaborator to integrate BioNeMo T5 LLMs into custom VAE architecture on Kubernetes.
Computational Scientist
Research Computing Center, University of Chicago
Mar 2021 - May 2022

Provided software development, training, and system administration for a Linux-based high performance computing (HPC) cluster serving University researchers

  • Benchmarked CPU and GPU performance on next-gen HPC cluster with NVIDIA A100 (MIG), AMD, and Intel hardware using CUDA and MPI.
  • Built multi-GPU molecular dynamics framework using JAX and MPI, scaling ensemble simulations beyond single-node limits.
  • Led interactive HPC workshops on SLURM, parallel Python/MPI, and high-performance computing concepts.
Postdoctoral Scholar
University of Chicago
Sep 2020 - Feb 2021

Conducted computational physics research spanning simulation development, software publication, and academic scholarship.

  • Published cross-platform Python & C++ simulation packages for electrodynamics and hydrodynamics, using CMake and pybind11
  • Co-authored over a dozen peer-reviewed publications with collaborators at the University of Chicago, Argonne National Laboratory, and partner academic institutions.

Education

University of Chicago
Chicago, IL
Sep 2014 - Aug 2020

PhD Physics

Computational physics research in Norbert Scherer's Lab. Thesis "Collective Electrodynamic Excitations and Non-conservative Dynamics in Optical Matter and Meta-atom Systems"

Georgia Institute of Technology
Atlanta, GA
Aug 2011 - May 2014

BS Physics, Minor in Mathematics

Computational physics research in Daniel Goldman's Complex Rheology And Biomechanics (CRAB) lab, studying the physical properties of granular materials.

Skills

AWS & Cloud
Kubernetes (EKS)ECSEC2RDSS3VPCTerraformArgoCDArgo Workflows
Databricks
Lakeflow Declarative PipelinesLakeflow JobsDelta Lake (OLTP)Lakebase (OLAP)Apache Spark
Python
NumPyScipyPandasPyTorchFastAPIMetaflowSQLAlchemyAlembicPanelStreamlitDashuvpixi
C++
CMakeEigenGSLCUDANVIDIA OptiXpybind11 & nanobind
Agentic AI
Claude CodeAWS BedrockDatabricks GenieAgents with Claude Agent SDK
Management and Leadership
Cloud budget managementLinear project managementStandard Operating Procedures authorshipTeaching and talent growth

Open Source

FPlanck
Python

FPlanck is a Python library for numerically solving the Fokker-Planck partial differential equation (also known as the Smoluchowski equation) in N dimensions using a matrix numerical method

MiePy
Python C++

MiePy is Python and C++ module to solve Maxwell's equations for a cluster of particles using the generalized multiparticle Mie theory (GMMT)

StokeD
Python

StokeD solves the Stokesian Dynamics equations for N interacting particles, a generalization of Brownian dynamics that includes hydrodynamic coupling interactions

Publications

Nature Communications
2025
Symmetry breaking-induced N-body electrodynamic forces in optical matter systems

John Parker, Spoorthi Nagasamudram, Curtis Peterson, Yanzeng Li, Sina Soleimanikahnoj, Stuart A Rice, Norbert F Scherer

PNAS
2025
ProT-VAE: Protein Transformer Variational AutoEncoder for Functional Protein Design

Emre Sevgen, Joshua Moller, Adrian Lange, John Parker, Sean Quigley, Jeff Mayer, Poonam Srivastava, Sitaram Gayatri, David Hosfield, Maria Korshunova, Micha Livne, Michelle Gill, Rama Ranganathan, Anthony B. Costa, Andrew L. Ferguson

ACS Nano
2025
Non-Equilibrium Dynamics and Non-Gaussian Fluctuations of an Optical Matter System Manifesting Pseudorotation

Shiqi Chen, John A. Parker, John Linderman, Curtis W. Peterson, Emmanuel Valenton, Stuart A. Rice, Andrew L. Ferguson, Norbert F. Scherer

npj Computational Materials
2024
PySAGES: flexible, advanced sampling methods accelerated with GPUs

Pablo F Zubieta Rico, Ludwig Schneider, Gustavo R Pérez-Lemus, Riccardo Alessandri, Siva Dasetty, Trung D Nguyen, Cintia A Menéndez, Yiheng Wu, Yezhi Jin, Yinan Xu, Samuel Varner, John A Parker, Andrew L Ferguson, Jonathan K Whitmer, Juan J de Pablo

The Journal of Physical Chemistry C
2024
Electrodynamic Interference and Induced Polarization in Nanoparticle-Based Optical Matter Arrays

Curtis Peterson, John Parker, Emmanuel Valenton, Yuval Yifat, Shiqi Chen, Stuart A Rice, Norbert F Scherer

arXiv
2024
Optical trapping with optical magnetic field and photonic Hall effect forces

Yanzeng Li, Emmanuel Valenton, Spoorthi Nagasamudram, John Parker, Marcos Perez, Uttam Manna, Mahua Biswas, Stuart A Rice, Norbert F Scherer

Molecular Systems Design & Engineering
2022
Understanding and design of non-conservative optical matter systems using Markov state models

Shiqi Chen, John A Parker, Curtis W Peterson, Stuart A Rice, Norbert F Scherer, Andrew L Ferguson

Nature Communications
2021
Data-driven reaction coordinate discovery in overdamped and non-conservative systems: application to optical matter structural isomerization

Shiqi Chen, Curtis W. Peterson, John Parker, Stuart A. Rice, Andrew L. Ferguson, Norbert F. Scherer

ACS Photonics
2021
Facile measurement of the rotation of a single optically trapped nanoparticle using the diagonal ratio of a quadrant photodiode

Yuval Yifat, John Parker, Tian-Song Deng, Stephen K. Gray, Stuart A. Rice, Norbert F. Scherer

Optica
2020
Optical matter machines: angular momentum conversion by collective modes in optically bound nanoparticle arrays

John Parker, Curtis W. Peterson, Yuval Yifat, Stuart A. Rice, Zijie Yan, Stephen K. Gray, Norbert F. Scherer

Physical Review Letters
2020
Excitation of nonradiating anapoles in dielectric nanospheres

John Parker, Hiroshi Sugimoto, Brighton Coe, Daniel Eggena, Minoru Fujii, Norbert F. Scherer, Stephen K. Gray, Uttam Manna

Cell Reports Physical Science
2020
Discrete pH-responsive plasmonic actuators via site-selective encoding of nanoparticles with DNA triple helix motif

Kyle J. Gibson, Aleksander Prominski, Margaret S. Lee, Timothy M. Cronin, John Parker, Yossi Weizmann

Physica Status Solidi B
2020
Designing "metamolecules" for photonic function: reduced back scattering

Tian-Song Deng, John Parker, Yutaro Hirai, Nolan Shepherd, Hiroshi Yabu, Norbert F. Scherer

Nano Letters
2019
Journal of Physical Chemistry C
2018
Dark plasmon modes in symmetric gold nanoparticle dimers illuminated by focused cylindrical vector beams

Tian-song Deng, John Parker, Yuval Yifat, Nolan Shepherd, Norbert F. Scherer

Nano Letters
2018
Dynamics of the optically directed assembly and disassembly of gold nanoplatelet arrays

Delphine Coursault, Nishant Sule, John Parker, Ying Bao, Norbert F. Scherer

Nature Communications
2018
Crossover from positive to negative optical torque in mesoscale optical matter

Fei Han, John Parker, Patrick McCormack, Yuval Yifat, Stephen K. Gray, Norbert F. Scherer, Zijie Yan

Light: Science & Applications
2018
Reactive optical matter: light-induced motility in electrodynamically asymmetric nano-scale scatterers

Yuval Yifat, Delphine Coursault, Curtis W. Peterson, John Parker, Ying Bao, Stephen K. Gray, Stuart A. Rice, Norbert F. Scherer

SPIE
2018
arXiv
2017
Nano Letters
2017
Selective induction of optical magnetism

Uttam Manna, Jung-hoon Lee, Tian-Song Deng, John Parker, Nolan Shepherd, Yossi Weizmann, Norbert F. Scherer